Compile Data Set for Download or QSAR
maximum 50k data
Found 404 of ic50 for VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S
having polymerids = 50000969,50002691 and
complexids = 50000903,50024737,50000735
LigandPNGBDBM50227255(CHEMBL102907)
Affinity DataIC50:  0.00810nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227481(CHEMBL286157)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227261(CHEMBL317044)
Affinity DataIC50:  0.0130nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227259(CHEMBL441428)
Affinity DataIC50:  0.0150nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227474(CHEMBL286598)
Affinity DataIC50:  0.0170nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227478(CHEMBL37402)
Affinity DataIC50:  0.0220nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227256(CHEMBL103806)
Affinity DataIC50:  0.0270nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227480(CHEMBL37899)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227476(CHEMBL204616)
Affinity DataIC50:  0.0330nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227479(CHEMBL35368)
Affinity DataIC50:  0.0450nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227473(CHEMBL1099207)
Affinity DataIC50:  0.0460nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227475(CHEMBL285868)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227257(CHEMBL321999)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50318494(3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50478489(CRAMBESCIDIN 816 HYDROCHLORIDE | Crambescidin 816 ...)
Affinity DataIC50:  0.150nMAssay Description:Antagonist activity at voltage-dependent L-type calcium channel in mouse neurobalstoma-rat glioma NG 108-15 hybrid cells assessed as inhibition of KC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50227262(CHEMBL105444)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50318494(3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of voltage-gated L-type Ca channel (species unknown)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227477(CHEMBL35123)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel of guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50029417(CHEMBL277363 | [4-(4-Methoxy-phenyl)-4H-benzo[b]py...)
Affinity DataIC50:  0.420nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50306490((+)-(S)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50:  0.420nMAssay Description:Displacement of [3H]nitrendipine from dihydropyridine receptor in rat cardiac membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306489((-)-(R)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50:  0.760nMAssay Description:Displacement of [3H]nitrendipine from dihydropyridine receptor in rat cardiac membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50469633(CHEMBL21906)
Affinity DataIC50:  0.780nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptors (CCRs) from rat cortex homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
LigandPNGBDBM50103634(CL-287389 | FK-235 | Nilvadipine | Nivadipine | SK...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50318494(3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...)
Affinity DataIC50:  1nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101813(CHEBI:31399 | Cilnidipine)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101813(CHEBI:31399 | Cilnidipine)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity against L-type calcium channel in SD rat thoracic aorta by Magnus methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101813(CHEBI:31399 | Cilnidipine)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in rat thoracic aorta ring assessed as effect on high K+ induced contraction by Magnus methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306490((+)-(S)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50:  1.48nMAssay Description:Displacement of [3H]nitrendipine from dihydropyridine receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228791(CHEMBL329897)
Affinity DataIC50:  1.5nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227260(CHEMBL319033)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50229256(CHEMBL73590)
Affinity DataIC50:  1.60nMAssay Description:Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228797(CHEMBL89260)
Affinity DataIC50:  1.70nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101817(Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]nitrendipine binding to calcium channels in the rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228807(CHEMBL2092901)
Affinity DataIC50:  2nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227967(CHEMBL78973)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of [3H]- Nitrendipine binding to L-type calcium channels of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227258(CHEMBL102498)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101817(Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101817(Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...)
Affinity DataIC50:  2.57nMAssay Description:Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of KCl-induced vasoconstriction after 30...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50101817(Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of KCl-induced vasoconstriction after 30...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50228801(CHEMBL89049)
Affinity DataIC50:  2.60nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50101815(CHEBI:7550 | Nicardipine)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channels of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228811(CHEMBL84906)
Affinity DataIC50:  2.70nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50475660(CHEMBL201566)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity against L-type calcium channel in SD rat thoracic aorta by Magnus methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50227254(CHEMBL318521)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of [3H]nitrendipine binding to guinea pig ileal longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228808(CHEMBL86415)
Affinity DataIC50:  3.10nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228810(CHEMBL89904)
Affinity DataIC50:  3.60nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50306489((-)-(R)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50:  3.62nMAssay Description:Displacement of [3H]nitrendipine from dihydropyridine receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50475658(CHEMBL201984)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against L-type calcium channel in SD rat thoracic aorta by Magnus methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50227246(CHEMBL3392282)
Affinity DataIC50:  4nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228804(CHEMBL89175)
Affinity DataIC50:  5.20nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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